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Center for Evidence-Based and Translational Medicine of Wuhan University
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A total of
22
result was found. Results that relate to
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靶向TGF-β信号通路的抑制剂在肝纤维化干预中的研究现状
WU Yalin
TIAN Sha
DOI:10.12173/j.issn.2097-4922.202511018
Hepatic fibrosis
TGF-β signaling pathway
Hepatic stellate cells
Inhibitors
Therapeutic
target
Molecular mechanisms
Drug delivery systems
Traditional Chinese medicine compounds
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基于网络药理学与分子对接探究小茴香治疗肝细胞癌的分子机制
DENG Xiaying
ZHAO Xiangxuan
DOI:10.12173/j.issn.2097-4922.202512059
Foeniculum vulgare
Network pharmacology
Network
target
s
Hepatocellular carcinoma
Mechanism of action
Molecular docking
Target
ed therapy
Natural products
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基于FAERS数据库分析扎维吉泮的安全性特征并比较其与CGRP靶向药物的安全性
XIE Jinlian
WANG Qing
ZHANG Xingfei
ZHANG Yaxin
WU Qian
MA Junlong
KUANG Yun
GUO Chengxian
DOI:10.12173/j.issn.2097-4922.202511062
Calcitonin gene-related peptide-
target
ed medication
Zavegepant
FAERS database
Signal mining
Disproportionality analysis
Bayesian confidence propagation neural network
Adverse events
Pharmacovigilance
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FKBP5功能及其在神经精神疾病中作用的研究进展
XING Jiaxin
ZHAO Mingyi
SONG Rui
LI Hong
DOI:10.12173/j.issn.2097-4922.202512035
FK506 binding protein 5
Neuropsychiatric disorders
Protein structure
Molecular function
Expression regulation
Therapeutic
target
Drug research
Clinical application prospects
Details
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非病毒载体在DNA药物递送领域的研究进展
LIU Hanxiao
YANG Xuehua
LIU Zhengping
MAO Kaifan
XUE Song
LI Dawei
TANG Xuan
DOI:10.12173/j.issn.2097-4922.202601050
Non-viral vectors
DNA drugs
Delivery systems
Target
ed delivery
Nanocarriers
Biocompatibility
Gene therapy
Clinical translation
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基于UPLC-Orbitrap-MS/MS和网络药理学探讨瓜蒌薤白汤治疗心肌梗死的作用机制研究
YAN Muxian
LAN Yikun
ZHOU Yaliang
TAN Wanchuang
LIN Junjie
DOI:10.12173/j.issn.2097-4922.202511027
Gualou Xiebai decoction
Myocardial infarction
Network pharmacology
Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry
Mechanism of action
Active components
Target
prediction
Details
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莲心季铵碱抗胰腺癌靶点筛选及药效评价:网络药理学预测与动物实验验证
QI Fei
CHEN Qi
DOI:10.12173/j.issn.2097-4922.202601003
Lotusine
Pancreatic cancer
Network pharmacology
Therapeutic
target
s
Molecular docking
Animal experiment
GO functional enrichment analysis
KEGG pathway enrichment analysis
Details
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