Objective  To study the chemical constituents of n-butanol fraction from ethanol extract of leaves of Cinnamomum cassia.

Methods  The leaves of Cinnamomum cassia were extracted and concentrated to obtain an extract, which was separated and purified using separation techniques such as Silica gel column chromatography, Sephdex LH-20 column chromatography and semi-preparative HPLC. The structures were identified by spectroscopic analysis.

Results  Six compounds were isolated from the leaves of Cinnamomum cassia, and identified as cinncassiol D1, vignaticol, (-)-(1R, 2R, 4S, 5R, 8S, 9S)-clovane-2,9,14-triol, (3S, 5R, 6R, 7E, 9S)-megastigman-7-ene-3,5,6,9-tetrol 3-O- β-D-glucopyranoside, tachioside and n-butyl-α-D-fructofuranoside.

Conclusion   Compounds 2-6 are all isolated from Cinnamomum cassia for the first time.

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