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Perioperative infection and antibacterial strategies in liver transplantation

Published on Apr. 04, 2025Total Views: 72 times Total Downloads: 27 times Download Mobile

Author: YU Miao 1 DU Hang 2 WANG Wenhua 2 HUANG Yuru 2

Affiliation: 1. Department of Pharmacy, Chongqing Fifth People's Hospital, Chongqing 400062, China 2. Department of Pharmacy, The Affiliated Dazu’s Hospital of Chongqing Medical University, Chongqing 402360, China

Keywords: Liver transplantation Perioperative period Infection Antibacterial drugs Immunosuppressants

DOI: 10.12173/j.issn.2097-4922.202410018

Reference: YU Miao, DU Hang, WANG Wenhua, HUANG Yuru. Perioperative infection and antibacterial strategies in liver transplantation[J]. Yaoxue QianYan Zazhi, 2025, 29(3): 525-530. DOI: 10.12173/j.issn.2097-4922.202410018.[Article in Chinese]

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Abstract

Liver transplant recipients often have low immunity due to their underlying diseases and the need for routine use of immunosuppressants to resist rejection after surgery, making them highly susceptible to perioperative infections. Bacterial and fungal infections are the main causes of high mortality after liver transplantation, so it is extremely important to strengthen the prevention of infection after liver transplantation. At present, there is no consensus on the prevention of infection during the perioperative period of liver transplantation. This article provides a brief review of the susceptibility factors, common infection sites, types of pathogens, and related antibacterial strategies for perioperative infection in liver transplantation, to provide reference for the prevention and use of antibiotics during the perioperative period of liver transplantation.

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