Objective  To explore the application of Chinese Drug-Related Problems Classification System in the pharmaceutical care of inpatients in neurology department.

Methods  A total of 222 inpatients admitted to the Department of Neurology of Affiliated Jinhua Hospital, Zhejiang University School of Medicine from March to June 2022 were selected as the study subjects, and the work records of clinical pharmacists were retrospectively analyzed. The drug-related problems (DRP) were sorted and analyzed according to the Chinese Drug-Related Problems Classification System. Binomial Logistic regression model was used to analyse the influencing factors of DRP.

Results  Among the 222 patients, 76 (34.23%) had DRP and a total of 104 DRP were found. The main problem type of DRP was treatment safety (39.42%). The involving objects of DRP were all doctors. In the severity assessment, the most involved level was “DRP reached the patient, but the patient was not harmed” (81.73%). The main reason for DRP was “choice of drugs” (67.31%), followed by “usage and dosage” (26.92%). A total of 62 (59.62%) DRP intervention schemes were accepted, and the overall acceptance rate of intervention schemes was 87.32%. In the end, 61 (58.65%) DRPs were resolved. The drug class with the largest number of DRP cases was antiplatelet drugs. Binomial Logistic regression analysis showed that the number of drug varieties [OR=1.097, 95%CI(1.030, 1.167)] was the influencing factor for the occurrence of DRP in neurology inpatients (P<0.05).

Conclusion  DRP is common in inpatients of neurology department. Chinese Drug-Related Problems Classification System is helpful for clinical pharmacists to review and sort pharmaceutical care data, summarize common problems and solving experience, and improve the effect of pharmaceutical care.

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