Biological activity assay can effectively guarantee the effectiveness and safety of traditional Chinese medicine, has a good application prospect in the quality detection of traditional Chinese medicine, and can be combined with other quality detection methods to establish a diversified quality control model of traditional Chinese medicine. However, there are also some shortcomings in the biological activity assay, which faces many challenges and needs further exploration and development. Based on the introduction of the basic contents of biological activity assay, the advantages and applications of biological activity assay compared with chemical analysis and traditional sensory evaluation methods in the quality detection of traditional Chinese medicine were discussed through searching and reading domestic and foreign papers in this article, in order to discuss the application and research progress of biological activity assay in the quality control of traditional Chinese medicine.

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