Gold is one of the mineral medicine and has a long history. "Calm the spirit, strengthen the bone marrow, clear five viscera, remove evil gas, and be like the immortal" was written on the "Annotation of Materia Medica", which was the first time to make clear its medicinal value. With the passage of time and the increase of related literature, people have a deeper understanding of the toxicity of gold. In order to avoid the harm caused by toxicity, the use frequency of gold is greatly reduced. There is still a lack of systematic research and sorting in modern researches, and the question of whether gold has medicinal value in Chinese patent medicine has not been deeply explored. Based on the description of ancient materia medica medical books, referring to the modern research results on "gold", this paper focused on the progress of medicinal properties of gold, ancient and modern applications and toxicity understanding, and on this basis, the medicinal value was analyzed, concluded and summarized, and the ancients' correct views on the use of gold was textually researched to provide the basis for further rational drug use in clinical and further development of its medicinal value.

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