With the continuous advancement of pharmaceutical quality supervision requirements and the rapid development of the pharmaceutical industry, the limitations of traditional detection methods in terms of timeliness, sensitivity, and intelligence have become increasingly prominent. There is an urgent need to establish highly efficient and reliable quality risk prevention and control systems through technological innovation. This study focused on the innovative applications of rapid detection technologies in pharmaceutical quality supervision. The technical characteristics of novel detection methods, including Raman spectroscopy, near-infrared spectroscopy, HPLC and hyphenated techniques, were systematically analyzed. Furthermore, the existing challenges and issues in China's pharmaceutical rapid detection technologies were investigated from perspectives encompassing biotechnology, chemical technology, spectroscopic technology, and hyphenated techniques. Corresponding strategies to promote the development of rapid detection technologies in China were proposed.

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