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Research progress on irradiation sterilization of traditional Chinese medicine

Published on Nov. 08, 2024Total Views: 159 times Total Downloads: 7 times Download Mobile

Author: YANG Chen 1, 2 ZHENG Yuxiao 1, 2 XU Xinyuan 1, 2 LI Yuehui 1, 2

Affiliation: 1. Hunan Academy of Traditional Chinese Medicine, Changsha 410013, China 2. Hunan University of Chinese Medicine, Changsha 410208, China

Keywords: Irradiation sterilization 60Co-γ ray Electron beam Traditional Chinese medicine Microorganisms Chemical constituents Effectiveness

DOI: 10.12173/j.issn.2097-4922.202404147

Reference: YANG Chen, ZHENG Yuxiao, XU Xinyuan, LI Yuehui.Research progress on irradiation sterilization of traditional Chinese medicine[J].Yaoxue QianYan Zazhi,2024, 28(2):331-340.DOI: 10.12173/j.issn.2097-4922.202404147.[Article in Chinese]

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Abstract

Sterilization is one of the key links in the production of traditional Chinese medicine, and it is also an important factor to ensure the safety, effectiveness and quality control of traditional Chinese medicine. Traditional sterilization techniques such as moist heat sterilization are limited in many cases due to their inherent shortcomings. In contrast, irradiation sterilization has attracted more and more attention due to its advantages of fast, efficient, strong sterilization and low cost. However, the chemical composition of traditional Chinese medicine is complex, due to the radioactivity and strong penetration of irradiation, after a certain dose of irradiation, its chemical composition and pharmacological activity may change. At present, there is still a lack of systematic research on the changes of chemical composition, effectiveness and safety of traditional Chinese medicine after irradiation sterilization. Based on the research status of 60Co-γ ray and electron beam irradiation sterilization in the sterilization of traditional Chinese medicine in recent years, this paper reviews the effects of irradiation on the effectiveness of traditional Chinese medicine, the detection methods of irradiation and the safety evaluation, in order to provide some reference for the subsequent application of irradiation sterilization of traditional Chinese medicine.

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References

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