Objective  To evaluate the effectiveness of medication therapy management (MTM) in patients with coronary heart disease (CHD) receiving home care.

Methods  A retrospective analysis was conducted on the data of CHD patients in the Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University from June 2023 to June 2024. According to different pharmaceutical service methods, patients were divided into a control group (receiving routine guidance) and a MTM group (adding MTM pharmaceutical services on the basis of routine medical care). The quality of life (SAQ score), medication adherence (MMAS-8 score), left ventricular function parameters (LVESD, and LVEDD, LVEF), serum NT pro BNP levels (NT-proBNP), major adverse cardiac events (MACE), and readmission were observed.

Results  A total of 200 patients with CHD were included in the study, with 109 in the control group and 91 in the MTM group. After 3 months of intervention, the scores of various dimensions of the SAQ scale, MMAS-8 score, and LVEF level in the MTM group were significantly higher than those in the control group (P<0.05), and the proportion of high compliance increased significantly (P<0.05); The levels of LVESD, LVEDD, and NT-proBNP were significantly lower than those in the control group (P<0.05). The total incidence of MACE in the MTM group was lower than that in the control group (P<0.05), but the difference in readmission rate was not statistically significant (P>0.05).

Conclusion  MTM services significantly improve the quality of life, medication adherence, and cardiac function parameters in CHD patients, while reducing the incidence of MACE.

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