Dry eye, also known as keratoconjunctivitis sicca, is clinically manifested as dry eyes, itching, burning, blurred vision and other symptoms, which seriously affects the life quality of patients. In recent years, the incidence of dry eye has increased year by year, and it has become one of the common clinical diseases in ophthalmology. At present, the treatment methods of dry eye mainly include drug treatment, surgical treatment and clinical nursing, among which drug is the most commonly used method for the treatment of dry eye. Therefore, this paper summarizes the application and research progress of clinical medication of dry eye based on permeation pathways and inflammatory pathways in recent years, so as to provide some ideas for the follow-up treatment of dry eye and drug development.

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