Chinese yam is a medicine-food homology traditional Chinese medicinal material, which exhibits the effects of tonifying the spleen and the stomach. Chinese yam is rich in bioactive components, including polysaccharides, flavonoids, saponins, fatty acids, sterols, phenolic acids, and more. Modern pharmacological studies have shown that Chinese yam exhibits various biological activities such as anti-inflammatory, immunomodulatory, antioxidant, and anti-fatigue. It can also regulate blood sugar and blood lipids, protect gastrointestinal health, and help prevent and treat age-related diseases. This article systematically reviews the research progress on the chemical composition and pharmacological effects of Chinese yam. Given that chronic atrophic gastritis (CAG) is a highly prevalent and severely harmful digestive disorder in China, this article focuses on analyzing the pharmacological effects of yam in the prevention and treatment of CAG. The research finds that the active ingredients in Chinese yam have a protective effect on CAG, providing new ideas and clues for the development of new drugs for the prevention and treatment of CAG based on Chinese yam.

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