Objective  To explore research hotspots of Aurantii Fructus Immaturus (AFI), to predict development trends of AFI and provide references for future research of AFI by bibliometrics.

Methods  The annual number of publications, journals, authors, countries and keywords of literature on the topic of AFI in CNKI and Web of Science Core Collection from January 1, 2004 to August 1, 2025 were visually analyzed. Excel 2019 was used to draw a distribution graph of the annual number of publications. VOSviewer 1.6.18 was used to draw a density view of core authors, a cluster view of keywords and a label view of keywords. CiteSpace 6.3.R1 was used to draw a co-occurrence map of countries and a highlight map of keywords.

Results  The study ultimately yielded 439 Chinese articles and 136 English articles. The Chinese Journal of Experimental Formulae had the highest number of publications (24 articles), while Food Chemistry had the highest number of publications in English (6 articles). The distribution of the annual number of publications and journals indicated that the field of AFI was developing rapidly and steadily. The co-occurrence analysis of authors demonstrated that 6 major teams led by Liu Zhenli, Lin Guimei, Luo Rong, Xiong Ying, Kim Gonsup and Liu Yuanyan had been formed domestically and abroad. The co-occurrence analysis of countries showed that researches were mainly distributed in China, South Korea, Brazil and the United States. The visualization analysis of keywords showed that quality evaluation, pharmacological effect with its mechanism, isolation and extraction of chemical constituents were hotspots of AFI.

Conclusion  The field of AFI is developing well. Two hotspots of AFI may be its quality evaluation and pharmacological effect with its mechanism in the future.

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