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Home Articles Vol 30,2026 No.3 Detail

Analysis of inorganic elements in Aconitum vilmorinianum Kom. by ICP-MS combined with chemometric methods

Published on Apr. 02, 2026Total Views: 20 times Total Downloads: 4 times Download Mobile

Author: ZHANG Yanming 1 LIU Yingying 2 LIU Yi 1 LIU Chengya 3 HUANG Lijia 1 PU Lianxin 1 LI Zhiyuan 1

Affiliation: 1. Yunnan Institute for Food and Drug Control, MIIT Public Service Platform for Industrial Technology Foundation, Kunming 650106, China 2. Yunnan Provincial Center for Food and Drug Inspection, Yunnan Provincial Vaccine Inspection Center, Kunming 650106, China 3. Yunnan Light and Textile Industry Vocational College, Kunming 650300, China

Keywords: Aconitum vilmorinianum Kom. Inorganic elements Microwave digestion Inductively coupled plasma mass spectrometry Chemometrics Content determination Analysis Geographical origin

DOI: 10.12173/j.issn.2097-4922.202512080

Reference: ZHANG Yanming, LIU Yingying, LIU Yi, LIU Chengya, HUANG Lijia, PU Lianxin, LI Zhiyuan. Analysis of inorganic elements in Aconitum vilmorinianum Kom. by ICP-MS combined with chemometric methods[J]. Yaoxue QianYan Zazhi, 2026, 30(3): 412-422. DOI: 10.12173/j.issn.2097-4922.202512080.[Article in Chinese]

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Abstract

Objective  Using inductively coupled plasma mass spectrometry (ICP-MS) combined with chemometric methods, to determine and analyze the content of 26 inorganic elements in Aconitum vilmorinianum Kom. from different regions, and to evaluate the influence of origin factors on the quality of Aconitum vilmorinianum Kom..

Methods  Microwave digestion-ICP-MS was used to determine the content of 26 inorganic elements in 57 batches of Aconitum vilmorinianum Kom. samples from different origins, and principal component and cluster analysis were combined for data processing.

Results  It showed that the contents of Cu, As and Pb in 14 batches exceeded the limits specified in the Chinese Pharmacopoeia (2025 edition). The origin factor resulted in differences in the content of 9 elements, 16 characteristic elements were ultimately identified related to the origin, and Aconitum vilmorinianum Kom. was classified by differences in elemental content.

Conclusion  The quality of Aconitum vilmorinianum Kom. is significantly affected by its geographical origin, and the analysis method of this inorganic element can be effectively used for its origin identification and quality assessment. Additionally, this study provides theoretical basis and scientific support for the production of high-quality Aconitum vil-morinianum Kom. in different regions.

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References

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