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Home Articles Vol 26,2023 No.12 Detail

One case of tremor induced by lasidipine combined with nimodipine in an elderly patient with hypertension

Published on Jan. 24, 2024Total Views: 1204 times Total Downloads: 474 times Download Mobile

Author: Qin LI 1, 2 Ying-Yan CHEN 3 Wen-Bin FANG 2 Wen-Yu LI 4

Affiliation: 1. Graduate School of Zhejiang Chinese Medical University, Hangzhou 310053, China 2. Department of Geriatric Medicine, Jinhua People's Hospital, Jinhua 321099, Zhejiang Province, China 3. Department of Gynaecology and Obstetrics, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China 4. Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China

Keywords: Tremors Lacidipine Nimodipine

DOI: 10.12173/j.issn.1008-049X.202312011

Reference: Qin LI, Ying-Yan CHEN, Wen-Bin FANG, Wen-Yu LI.One case of tremor induced by lasidipine combined with nimodipine in an elderly patient with hypertension[J].Zhongguo Yaoshi Zazhi,2023, 26(12): 487-490.DOI: 10.12173/j.issn.1008-049X.202312011.[Article in Chinese]

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Abstract

An 80-year-old male patient was hospitalized with tremor. Through the detailed collection of medical history and perfect examination, it was determined that the disease was caused by lasidipine nimodipine, tremor disappeared after withdrawal, and no recurrence after 1 year follow-up. Although tremor does not affect life, it directly affects the quality of life of patients, and the awareness and attention of this adverse reaction should be improved clinically.

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References

1.许甜甜. 美托洛尔对自发性高血压大鼠血管老化的防治作用及机制研究[D]. 湖北宜昌: 三峡大学, 2023.

2.凃玲. 老年患者药物不良反应[J]. 医学新知, 2018, 28(3): 246-247. [Tu L. Adverse drug reactions in elderly patients[J]. Yixue Xinzhi Zazhi, 2018, 28(3): 246-247.] DOI: 10.3969/j.issn.1004-5511.2018.03.005.

3.van de Wardt J, van der Stouwe AMM, Dirkx M, et al. Systematic clinical approach for diagnosing upper limb tremor[J]. J Neurol Neurosurg Psychiatry, 2020, 91(8): 822-830. DOI: 10.1136/jnnp-2019-322676.

4.杨华, 魏晶, 王嘉仡, 等. 药品不良反应/事件报告评价方法研究[J]. 中国药物警戒, 2009, 6(10): 581-584. [Yang H, Wei J, Wang JG, et al. Study on evaluation methods for reporting adverse drug reactions/events[J]. China Pharmacovigilance, 2009, 6(10): 581-584.] DOI: 10.3969/j. issn.1672-8629.2009.10.002.

5.陈静, 成华. 伐昔洛韦分散片致血液透析患者神经系统不良反应1例[J]. 药物流行病学杂志, 2023, 32(5): 596-600. [Chen J, Cheng H. One case of adverse neurological reaction in hemodialysis patients caused by valaciclovir dispersible tablets[J]. Chinese Journal of Pharmacoepidemiology, 2023, 32(5): 596-600.] DOI: 10.19960/j.issn.1005-0698.202305015.

6.罗艳. 钙通道阻滞药的临床研究及不良反应分析[J]. 中国临床药理学杂志, 2015, 31(6): 467-469. [Luo Y. Clinical study and adverse reaction analysis of calcium channel blockers[J]. Chinese Journal of Clinical Pharmacology, 2015, 31(6): 467-469.] DOI: 10.13699/j. cnki.1001-6821.2015.06.020.

7.虞珑. 拉西地平致全身肌肉震颤1例[J]. 医学信息, 2014, (26): 654. [Yu L. One case of systemic muscle tremor caused by lacidipine[J]. Medical Information, 2014, (26): 654. ] DOI: 10.3969/j. issn.1006-1959.2014.26.857.

8.宋银霞, 刘晶. 尼莫地平致全身肌肉不自主震颤1例 [J]. 中国新药杂志, 1995, (2): 44. [Song YX, Liu J. One case of involuntary muscle tremor caused by nimodipine[J]. Chinese Journal of New Drugs, 1995, (2): 44.] DOI: CNKI: SUN: ZXYZ.0.1995-02-016.

9.Mitsuda M, Nomoto M, Iwata S. Effects of beta-blockers and nicardipine on oxotremorine-induced tremor in common marmosets[J]. Jpn J Pharmacol, 1999, 81(2): 244-246. DOI: 10.1254/jjp.81.244.

10.Pileblad E, Carlsson A. In vivo effects of the Ca2+-antagonist nimodipine on dopamine metabolism in mouse brain[J]. Journal of Neural Transmission, 1986, 66(3-4): 171-187. DOI: 10.1007/BF01260912.

11.Pardal MF, Pardal JF, Micheli F. Aggravation of Parkinson's disease by cinnarizine[J]. J Neurol Neurosurg Psychiatry, 1988, 51(1): 158-159. DOI: 10.1136/jnnp.51.1.158-c.

12.Mena MA, de Yébenes MJG, Tabernero C, et al. Effects of calcium antagonists on the dopamine system[J]. Clin Neuropharmacol, 1995, 18(5): 410-426. DOI: 10.1097/00002826-199510000-00004.

13.Brücke T, Wöber C, Podreka I, et, al. D2 receptor blockade by flunarizine and cinnarizine explains extrapyramidal side effects. a spect study[J]. J Cereb Blood Flow Metab, 1995, 15(3): 513-518. DOI: 10.1038/jcbfm.1995.63.

14.李媛媛, 王亮, 曲恒燕, 等. 基因多态性对比卡鲁胺药代动力学的影响并比较不同剂型比卡鲁胺的药代动力学特征[J]. 中国临床药理学杂志, 2018, 34(9): 1056-1059. [Li YY, Wang L, Qu HY, et al. Comparison of the effects of gene polymorphism on the pharmacokinetics of carlumide and comparison of the pharmacokinetic characteristics of different dosage forms of carlumide[J]. Chinese Journal of Clinical Pharmacology, 2018, 34(9): 1056-1059.] DOI: 10.13699/j.cnki.1001-6821. 2018.09.014.

15.吴华. CYP3A4酶相关的临床药物相互作用[J]. 中国药物警戒, 2016, 13(5): 286-290. [Wu H. Clinical drug interactions related to CYP3A4 enzyme[J]. Chinese Pharmacovigilance, 2016, 13(5): 286-290.] DOI: CNKI: SUN:YWJJ.0.2016-05-010.

16.Thanvi B, Treadwell S. Drug induced parkinsonism: a common cause of parkinsonism in older people[J]. Postgrad Med J, 2009, 85(1004): 322-326. DOI: 10.1136/pgmj.2008.073312.

17.张文波, 王宇卉. 震颤的诊断和鉴别诊断策略[J]. 世界临床药物, 2012, 33(10): 586-590. [Zhang WB, Wang YH. Diagnosis and differential diagnosis strategies for tremor[J]. World Clinical Pharmacology, 2012, 33(10): 586-590.] DOI: CNKI:SUN:GWHH.0.2012-10-003.

18.Bondon-Guitton E, Perez-Lloret S, Bagheri H, et al. Drug-induced parkinsonism: a review of 17 years' experience in a regional pharmacovigilance center in France[J]. Mov Disord, 2011, 26(12): 2226-2231. DOI: 10.1002/mds.23828.

19.楼小琳, 张小梅. 药源性锥体外系不良反应研究的新进展[J]. 北京医学, 1999, 21(5): 297. [Lou XL, Zhang XM. New progress in the study of drug-induced extrapyramidal adverse reactions[J]. Beijing Medical Journal, 1999, 21(5): 297. ] DOI: CNKI: SUN: BJYX.0. 1999-05-018.

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