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基于FAERS数据库分析扎维吉泮的安全性特征并比较其与CGRP靶向药物的安全性

XIE Jinlian WANG Qing ZHANG Xingfei ZHANG Yaxin WU Qian MA Junlong KUANG Yun GUO Chengxian

DOI：10.12173/j.issn.2097-4922.202511062

Calcitonin gene-related peptide-targeted medication Zavegepant FAERS database Signal mining Disproportionality analysis Bayesian confidence propagation neural network Adverse events Pharmacovigilance
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中药治疗轻度认知障碍的系统评价与Meta分析

ZENG Baoqi TANG Chunbian DOU Lin SHENG Feng SUN Feng

DOI：10.12173/j.issn.2097-4922.202511017

Traditional Chinese medicine Cognitive function Mild cognitive impairment Activities of daily living Meta-analysis Randomized controlled trial Adverse reaction Safety
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干姜化学成分与药理作用分析

DUAN Xiaonan DI Qing YU Ran SUN Cuige ZHENG Xiaonan SUN Guyue ZHAO Xiangxuan

DOI：10.12173/j.issn.2097-4922.202512025

Zingiberis rhizoma Chemical composition Pharmacological effect Diphenylheptanes Flavonoids Anti-tumor Antioxidant Lowering blood sugar
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FKBP5功能及其在神经精神疾病中作用的研究进展

XING Jiaxin ZHAO Mingyi SONG Rui LI Hong

DOI：10.12173/j.issn.2097-4922.202512035

FK506 binding protein 5 Neuropsychiatric disorders Protein structure Molecular function Expression regulation Therapeutic target Drug research Clinical application prospects
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疏肝解郁中药防治肥胖症的作用机制与应用研究概况

DOU Xia LI Yingmei LIU Wenrong XU Meng YANG Xinrong JIN Ziming

DOI：10.12173/j.issn.2097-4922.202512091

Obesity Traditional Chinese medicine for soothing the liver and relieving depressio Mechanism of action Lipid metabolism Insulin resistance Chronic inflammation
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非病毒载体在DNA药物递送领域的研究进展

LIU Hanxiao YANG Xuehua LIU Zhengping MAO Kaifan XUE Song LI Dawei TANG Xuan

DOI：10.12173/j.issn.2097-4922.202601050

Non-viral vectors DNA drugs Delivery systems Targeted delivery Nanocarriers Biocompatibility Gene therapy Clinical translation
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中药固体制剂溶出度分析方法研究进展

JIA Ziyi SUN Wei XIONG Haoshu ZHANG Shunnan

DOI：10.12173/j.issn.2097-4922.202510006

Traditional Chinese medicine Solid preparations Dissolution Detection technology Data analysis Formulation optimization Quality control Multi-dimensional evaluation
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基于Apriori算法、网络药理学及分子对接分析含黄芪-知母药对方剂治疗慢性心力衰竭的作用机制

ZHANG Mengqian PANG Jianying WANG Chaohui HOU Jiahao ZHANG Yajing LI Jing SONG Yongxing MA Donglai

DOI：10.12173/j.issn.2097-4922.202512064

Chronic heart failure Astragali Radix-Anemarrhenae Rhizoma Herb pair Apriori algorithm Network pharmacology Molecular docking
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基于UPLC-Orbitrap-MS/MS和网络药理学探讨瓜蒌薤白汤治疗心肌梗死的作用机制研究

YAN Muxian LAN Yikun ZHOU Yaliang TAN Wanchuang LIN Junjie

DOI：10.12173/j.issn.2097-4922.202511027

Gualou Xiebai decoction Myocardial infarction Network pharmacology Ul-tra-performance liquid chromatography-orbitrap tandem mass spectrometry Mechanism of action Active components Target prediction
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莲心季铵碱抗胰腺癌靶点筛选及药效评价：网络药理学预测与动物实验验证

QI Fei CHEN Qi

DOI：10.12173/j.issn.2097-4922.202601003

Lotusine Pancreatic cancer Network pharmacology Therapeutic targets Molecular docking Animal experiment GO functional enrichment analysis KEGG pathway enrichment analysis
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双酚A通过BPA/HRH1轴调控特异性皮炎免疫微环境的机制研究

LI Chunhua LIANG Qinghua FU Qinqin ZHAO Kaizheng LU Jun

DOI：10.12173/j.issn.2097-4922.202512054

Bisphenol A Atopic dermatitis Endocrine disruptor Immune microenvironment Histamine receptor H1 Lymphocyte-specific protein tyrosine kinase Platelet-activating factor receptor
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瓜蒌薤白半夏汤促进线粒体自噬改善心肌缺氧/复氧损伤的物质基础与机制

ZHU Jiaxuan SONG Xiansheng YANG Ziqi XIAN Leyao ZHOU Hua HE Fan HUANG Yufeng

DOI：10.12173/j.issn.2097-4922.202602014

Gualou Xiebai Banxia decoction Chrysoeriol Hypoxia/reoxygenation myocardial cell injury Mitophagy Apoptosis Caspase-3 Parkin FUNDC1
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黄蜀葵花直服饮片与传统饮片中金丝桃苷在正常及肾病综合征大鼠体内的药代动力学比较研究

NIU Kailin LUO Heng ZHOU Jing BAI Xiaolu WEN Qing CHEN Chu WU Yan ZHANG Hong MENG Huix-in ZHANG Lei

DOI：10.12173/j.issn.2097-4922.202504070

Abelmoschus manihot (L.) Medic. Hyperoside Nephrotic syndrome Directly taken decoction pieces Traditional decoction pieces HPLC-QqQ/MS Pharmacokinetics Drug metabolism Rats
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不同产地烈香杜鹃中无机元素的分析与评价

XU Sisi ZHANG Rui WANG Kefeng FAN Minxia TIAN Yongqiang

DOI：10.12173/j.issn.2097-4922.202511039

Rhododendron anthopogonoides Maxim. Inorganic elements ICP-AES ICP-MS FAAS
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维药罗勒子总多酚提取工艺优化及体外抗氧化活性评价

WANG Lei WANG Fanhong CHEN Mo LI Zhen

DOI：10.12173/j.issn.2097-4922.202601020

Ocimum basilicum L. seeds Total polyphenols Ultrasonic-assisted extraction Orthogonal experiment Single-factor test DPPH ABTS Antioxidant activity
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