Objective  To evaluate the impact of the WeChat platform health management model combined with low-dose atorvastatin on lipid and glucose profiles, quality of life, and negative emotions in patients with metabolic syndrome and obesity.

Methods  The data of obese patients with metabolic syndrome who were treated at Shangyu People's Hospital of Shaoxing from June 2022 to June 2023 were retrospectively analyzed. The patients were divided into a control group and an experimental group according to their out- of- hospital health management methods. The control group received atorvastatin combined with conventional health management treatment, and the experimental group received atorvastatin combined with a health management model based on the WeChat platform. The blood glucose and lipid-related indicators were compared between the two groups before and 3 months and 6 months after intervention. Negative emotions and quality of life were compared before and 6 months after intervention, and self-management ability was compared 6 months after intervention.

Results  A total of 160 patients were included in the study, with 85 patients in the control group and 75 patients in the experimental group. After the intervention, the fasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPBG), glycated hemoglobin (HbA1c), low- density lipoprotein (LDL-C), triglyceride (TG) and total cholesterol (TC) of the two groups of patients at 3 months and 6 months) were significantly lower than before intervention, and the above indicators of the experimental group were lower than those of the control group (P<0.05); while high-density lipoprotein (HDL-C) was significantly higher than that before intervention, and HDL-C in the observation group was higher than that of the control group (P<0.05). Compared with pre-treatment, the anxiety self-rating scale (SAS) and depression self-rating scale (SDS) scores were siginficantly lower, and various quality of life scores for both groups significantly higher 6 months after intervention (P<0.05), and the self- management ability of the experimental group was significantly higher than that of the control group (P<0.05).

Conclusion  Low-dose atorvastatin combined with the WeChat platform health management model effectively improves lipid profiles, blood glucose, negative emotions, self-management behavior, and quality of life in patients with metabolic syndrome and obesity, which is worthy of clinical promotion.

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