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Research progress on chemical composition and pharmacological activity of polysaccharides and saponins of Polygonatum rhizoma

Published on Apr. 29, 2025Total Views: 88 times Total Downloads: 27 times Download Mobile

Author: QING Yu 1, 2, 3 FAN Minxia 1, 3, 4 CHEN Guilin 1, 2, 3, 4 HU Guangwan 1, 2, 3, 4

Affiliation: 1. CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, China 2. University of Chinese Academy of Sciences, Beijing 100049, China 3. Sino-Africa Joint Research Center, Chinese Academy of Sciences, Wuhan 430074, China 4. Hubei Jiangxia Laboratory, Wuhan 430200, China

Keywords: Polygonatum rhizoma Polysaccharide of Polygonatum rhizoma Saponin of Polygonatum rhizoma Chemical composition Pharmacological activity

DOI: 10.12173/j.issn.2097-4922.202501058

Reference: QING Yu, FAN Minxia, CHEN Guilin, HU Guangwan. Research progress on chemical composition and pharmacological activity of polysaccharides and saponins of Polygonatum rhizoma[J]. Yaoxue QianYan Zazhi, 2025, 29(4): 681-697. DOI: 10.12173/j.issn.2097-4922.202501058.[Article in Chinese]

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Abstract

Polygonatum rhizoma is a herbaceous plant that can be used as both medicine and food. Its main active ingredients include polygonatum rhizoma polysaccharide and polygonatum rhizoma saponin. Among them, polygonatum rhizoma polysaccharide is a kind of miscellaneous sugar, mainly composed of monosaccharides such as glucose, mannose, fructose, galacturonic acid, galactose, glucuronic acid and arabinose, and has antioxidant, immune-enhancing, anti-tumor, anti-inflammatory and antiviral effects. Polygonatum rhizoma saponin mainly includes steroidal saponin and triterpenoid saponin, which has significant effects such as anti-inflammatory, anti-tumor, hypolipidemic, hypoglycemic and anti-aging effects. In recent years, with the increasing attention paid to natural medicinal resources, Polygonatum rhizoma has gradually become a hot topic of research due to its rich active ingredients and diverse biological effects. Although relevant research is increasing, there is still a lack of systematic and in-depth summary and induction of these two types of components. Based on this, this paper intends to organize and analyze the research progress of polygonatum rhizoma polysaccharide and saponin on the basis of existing research results, in order to provide theoretical support and reference basis for their further basic research and industrial application.

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