Objective  To conduct a visual analysis of the relevant literature on the chemical components and pharmacological effects of Angelica sinensis using bibliometric methods, to reveal more clearly the development patterns, research hotspots and trends in this field, and to provide a reference basis for in-depth research and clinical application of Angelica sinensis.

Methods  Literature related to the chemical constituents and pharmacological effects of Angelica sinensis from January 1995 to December 2025 was retrieved in five databases: China National Knowledge Infrastructure (CNKI), VIP Chinese Journal Service Platform, WanFang Data Knowledge Service Platform, Web of Science (WOS), and PubMed. The annual publication volume, authors, institutions, and keywords of the literature were visually analyzed using CiteSpace and VOSviewer software, and author collaboration network maps, institutional density views, keyword co-occurrence, and clustering visualization maps were generated. Additionally, the co-citation analysis function of VOSviewer was utilized to identify important literature and journal sources in the field of Angelica sinensis research, thereby assisting in analyzing the research progress in this area.

Results A total of 737 Chinese literature and 1,263 English literature were included. The main publishing institutions were traditional Chinese medicine universities, with Beijing University of Chinese Medicine and Gansu University of Chinese Medicine having the highest number of publications. The research hotspots focused on major chemical components such as ferulic acid, ligustilide, and Angelica sinensis polysaccharides, as well as the pharmacological mechanism.

Conclusion With the development of science and technology, the techniques for the extraction, separation, and identification of traditional Chinese medicine are continuously being improved. The pharmacological effects and mechanisms of Angelica sinensis and its active components will be further elucidated, and related experimental studies will progressively move toward systematic and in-depth directions.

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