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Establishment and clinical application of standardized management for oral drug administration through nasal feeding

Published on Jul. 31, 2024Total Views: 1127 times Total Downloads: 250 times Download Mobile

Author: LIU Yu 1 CHEN Donglin 2 HUANG Liyun 1 WANG Baiqiao 1

Affiliation: 1. Department of Pharmacy, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China 2. Department of Pharmacy, Haikou Affiliated Hospital of Central South University Xiangya School of Medical, Haikou 570208, China

Keywords: Nasal feeding administration of oral drugs Management standards Awareness Rationality Evidence-based practice

DOI: 10.12173/j.issn.1008-049X.202404020

Reference: LIU Yu, CHEN Donglin, HUANG Liyun, WANG Baiqiao.Establishment and clinical application of standardized management for oral drug administration through nasal feeding[J].Zhongguo Yaoshi Zazhi,2024, 27(7):1210-1219.DOI: 10.12173/j.issn.1008-049X.202404020.[Article in Chinese]

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Abstract

Objective  To establish a standardized management system for oral drug administration through nasal feeding and observe its clinical implementation effect.

Methods  Authoritative books and drug instructions at home and abroad were consulted, and relevant literature at home and abroad was searched to evaluate the situation of nasal feeding administration, so as to determine the unreasonable factors in clinical nasal feeding administration. Relevant keywords were used to search in the databases, in order to determine the standardized literature and screen the best evidence for the standardized management of patients with intranasal administration of oral drugs. The GRADE grading method was used, the evidence was graded, the comprehensive evidence formed the nasal feeding administration management standard, and evidence-based practice was carried out. The recognition rates of nasal feeding, overall correct answer rates, rational results of medication and adverse events of medical staff and pharmacists before and after the implementation of management standards were compared.

Results  Compared to before the implementation of the management standard for oral drug administration through nasal feeding, after the establishment and implementation of the management standard for oral drug administration through nasal feeding, the awareness rate and overall accuracy rate of nasal feeding among medical staff and pharmacists increased, the unreasonable situations of nasal feeding administration decreased, the adverse events of nasal feeding administration decreased, and there were statistical significant differences between groups before and after implementation (P<0.05).

Conclusion  The establishment of standardized management for oral drug administration through nasal feeding has a positive effect on improving the awareness of medical staff towards nasal feeding, reducing the occurrence of unreasonable nasal feeding and adverse events.

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References

1.周宬玥, 蔡和平, 罗志红, 等. 某儿童医院重症监护室患儿鼻饲给药合理性分析[J]. 儿科药学杂志, 2022, 28(3): 13-17. [Zhou CY, Cai HP, Luo ZH, et al. Application rationality of nasogastric dosing for children in intensive care unit of a children's hospital[J]. Journal of Pediatric Pharmacy, 2022, 28(3): 13-17.] DOI: 10.13407/j.cnki.jpp.1672-108X.2022.03.004.

2.张莹, 谷清, 刘丽宏. 重症监护病房患者鼻饲给药情况及合理性分析[J]. 临床药物治疗杂志, 2021, 19(4): 58-62. [Zhang Y, Gu Q, Liu LH. Analysis on the usage and rationality of medication administration through nasal feeding tubes for intensive care unit patients[J]. Clinical Medication Journal, 2022, 28(3): 13-17.] DOI: 10.3969/j.issn.1672-3384.2021.04.012.

3.White R, Bradnam V. Handbook of Drug Administration via Enteral Feeding Tubes[M]. UK: RPS Pubishing, 2007: 1-548.

4.国家药典委员会. 中华人民共和国药典·临床用药须知: 化学卷和生物制品卷[S]. 北京: 中国医药科技出版社, 2010: 1-1128.

5.陈新谦, 金有豫, 汤光, 主编. 新编药物学[M]. 北京: 人民卫生出版社, 2011: 34-831.

6.刘煜, 任少琳, 张秋萍, 等. 饲管给药现状调查以及合理性分析[J]. 中南药学, 2017, 15(2): 242-245. [Liu Y, Ren SL, Zhang QP, et al. Present situation and evaluation of rationality for tube feeding[J]. Central South Pharmacy, 2017, 15(2): 242-245.] DOI: 10.7539/j.issn.1672-2981.2017.02.025.

7.白娟, 王亚琦, 徐丽婷, 等. 某院鼻饲给药情况及合理性调查分析[J]. 中国药物与临床, 2023, 23(2): 99-103. [Bai J, Wang YQ, Xu LT, et al. Current situation and rationality of nasogastric administration of medications in a hospital[J]. Chinese Remedies & Clinics, 2023, 23(2): 99-103.] DOI: 10.11655/zgywylc2023.02.008.

8.赵娟, 陈岩, 张标, 等. 临床药师在提高护理人员鼻饲给药合理性中的作用[J]. 医药导报, 2019, 38(1): 107-110. [Zhao J, Chen Y, Zhang B, et al. The role of clinical pharmacists in improving the rationality of nasal feeding for nursing staff[J]. Herald of Medicine, 2020, 7(89): 71-72.] DOI: 10.3870/j.issn.1004-0781.2019.01.025.

9.Volkert D, Berner YN, Berry E, et al. ESPEN guidelines on enteral nutrition: geriatrics[J]. Clin Nutr, 2006, 25(2): 330-360. DOI: 10.1016/j.clnu.2006.01.012.

10.Williams NT. Medication administration through enteral feeding tubes[J]. Am J Health Syst Pharm, 2008(65): 2347-2357. DOI: 10.2146/ajhp080155.

11.刘春雨, 李健, 苏兰, 等. 管喂给药的药物选择[J]. 华西医学, 2008, 23(2): 426-427. [Liu CY, Li J, Su L, et al. Drug selection for tube feeding administration[J]. West China Medical Journal, 2008, 23(2): 426-427.] DOI: 10.3969/j.issn.1002-0179.2008.02.146.

12.中华医学会. 临床诊疗指南-肠外肠内营养学分册 [M]. 北京: 人民卫生出版社, 2009: 1-128.

13.Bankhead R, Boullata J, Brantley S, et al. Enteral nutrition practice recommendations[J]. JPEN J Parenter Enteral Nutr, 2009, 33(2): 122-167. DOI: 10.1177/ 0148607108330314.

14.McClave SA, Martindale RG, Vanek VW, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: society of critical care medicine (SCCM) and American society for parenteral and enteral nutrition (ASPEN)[J]. JPEN J Parenter Enteral Nutr, 2009, 33(3): 277-316. DOI: 10.1177/0148607109335234.

15.Higgins J. Cochrane handbook for systematic reviews of intervention[EB/OL]. (2011-03-01) [2014-04-01]. http// www.handbook.cochrane.org.

16.Proehl JA, Heaton K, Naccarato MK, et al. Emergency nursing resource: gastric tube placement verification[J]. Emerg Nurs, 2011, 37(4): 357-362. DOI: 10.1016/j.jen. 2011.04.011.

17.Bell L. Prevention of Aspiration[EB/OL]. (2011-11-01) [2014-02-16]. http://www.aacn.org/WD/practice/docs/practicealerts/aacn-aspiration-practice-alert.pdf.

18.杨帆, 欧阳华, 黄婉彬. 重症监护室91例患者鼻饲管给药的合理性分析[J]. 中国新药杂志, 2012, 21(8): 938-942. [Yang F, Ouyang H, Huang WB. Analysis of 91 patients for the rational use of drug through nasal feeding tube in intensive care unit[J]. Chinese Journal of New Drugs, 2012, 21(8): 938-942.] DOI: CNKI:SUN:ZXYZ.0. 2012-08-029.

19.NPSA. Reducing the harm caused by misplaced nasogastric feeding tubes in adults, children and infants[EB/OL]. (2011-03-10) [2014-02-12]. http//www.nrls.npsa.nhs.uk/alerts.

20.甄晓慧, 甄荣荣, 单悌超, 等. 管饲给药的临床评估与操作建议[J]. 中国新药与临床杂志, 2017, 36(2): 114-120. [Zhen XH, Zhen RR, Dan DC. Assessment and administration methods of drug administrating via enteral feeding tubes[J]. Chinese Journal of New Drugs and Clinical Remedies, 2017, 36(2): 114-120.] DOI: 10.14109/j.cnki.xyylc.2017.02.012.

21.中华医学会消化病学分会胃肠动力学组, 外科学分会结直肠肛门外科学组.中国慢性便秘的诊治指南(2013, 武汉)[J]. 胃肠病学, 2013, 18(10): 605-612. DOI: 10.3760/cma.j.issn.0254-1432.2013.05.002.

22.高玲娜, 杜雪亭, 朱小丽, 等. 神经外科鼻饲给药情况分析与改进[J]. 医药导报, 2021, 40(2): 265-268. [Gao LN, Du XT, Zhu XL, et al. Analysis and improvement of nasal feeding in neurosurgery[J]. Herald of Medicine, 2021, 40(2): 265-268.] DOI: 10.3870/j.issn.1004-0781. 2021.02.022.

23.张晏洁, 流小舟, 曾丽娟, 等. 临床药师参与多学科合作的骨肉瘤患者大剂量甲氨蝶呤药学监护的效果评价 [J]. 中国药学杂志, 2021, 56(19): 1612-1616. [Zhang YJ, Liu XZ, Zeng LJ, et al. Evaluation of clinical pharmacists participating in multi-disciplinary cooperation in the pharmaceutical care of osteosarcoma patients with high-dose methotrexate[J]. Chinese Pharmaceutical Journal, 2019, 56(19): 1612-1616.] DOI: 10.11669/cpj. 2021.19.014.

24.郭敏, 刘金玉, 曾露, 等. 某院在推进处方审核系统中给药途径存在的问题与对策[J]. 中国医院药学杂志, 2021, 41(12): 1258-1263. [Guo M, Liu JY, Zeng L, et al. Problems and countermeasures of drug administration in promoting prescription review system in a hospital[J]. Chinese Journal of Hospital Pharmacy, 2021, 41(12): 1258-1263.] DOI: 10.13286/j.1001-5213.2021.12.15.

25.王子民, 姜德春, 刘琛, 等. 临床药师对我院鼻饲医嘱前置审核规则的干预效果分析[J]. 实用药物与临床, 2020, 23(6): 557-560. [Wang ZM, Jiang DC, Liu C, et al. Analysis of intervention effect of clinical pharmacists on pre-review rules of nasal feeding orders in our hospital[J]. Practical Pharmacy and Clinical Remedies, 2019, 23(6): 557-560.] DOI: 10.14053/j.cnki.ppcr.202006019.

26.孙雨菁, 李琰华, 李俊伟. 抗高血压药物不同缓控释剂型在鼻饲中的应用[J]. 中华全科医学, 2021, 19(1): 108-112. [Sun YJ, Li YH, Li JW. Application of different slow-controlled release formulations of antihypertensive drugs in nasal feeding[J]. Chinese Journal of General Practice, 2019, 19(1): 108-112.] DOI: 10.16766/j.cnki.issn.1674-4152.001743.

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