Objective To evaluate the efficacy of low molecular weight heparin (LMWH) combined with LEARNS mode of resistance band training (RBT) in the prevention of deep vein thrombosis (DVT) after hip arthroplasty and to investigate its effects on patients' blood hypercoagulability, hip function and daily living ability.
Methods Patients undergoing posterior approach hip replacement surgery in the Department of Orthopedic Trauma of The Second Affiliated Hospital of Wenzhou Medical University from January 2023 to January 2024 were selected as study subjects, and the patients were randomly and equally divided into the control group (LMWH combined with conventional care) and the experimental group (LMWH combined with RBT in LEARNS mode) according to the random number table method. The efficacy assessment was divided into short-term efficacy (14 days) and long-term efficacy (12 weeks), and the primary observation of the study was the incidence of DVT at 14 d of the outcome, and the secondary observation indexes were the changes in coagulation function at 14 d [activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen (FIB), prothrombin time (TT), and D-dimer (DD)], Harris hip scores (HHS) and Barthel index (BI) scores of the daily living ability scale at 4 weeks and 12weeks after sugery.
Results A total of 106 cases were included in the study, and there were 53 cases the control group and 53 cases in the experimental group.The incidence of DVT at 14 d was significantly lower in the experimental group than in the control group (P<0.05). The differences in preoperative APTT, PT, FIB, TT and DD between the two groups were not statistically significant (P>0.05). At 14 d postoperatively, APTT, PT and TT increased and FIB and DD decreased in the experimental group compared with the preoperative period (P<0.05); PT and TT increased and FIB and DD decreased in the control group compared with the preoperative period (P<0.05). In addition, APTT, PT and TT of the experimental group were higher than those of the control group at 14 d postoperatively (P<0.05), while the difference in FIB and DD between the two groups was not statistically significant (P>0.05). At 4 weeks and 12 weeks postoperatively, the HHS scores and BI scores of the experimental group were higher than those of the control group (P<0.05).
Conclusion LMWH combined with LEARNS-RBT can improve coagulation function in patients after hip replacement surgery and reduce the incidence of lower limb DVT. Furthermore, LEARNS-RBT can also enhance patients' hip joint function and daily living ability.
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