Effects of Anemarrhenae Rhizoma on the dissolution of 6 inorganic elements in Gypsum Fibrosum under different compatibility ratio based on grey correlation analysis and TOPSIS model

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Author: Xiao-Dong YANG  Guo-Wei LI Wen-Ping WU Xiao-Lin LIU Xiang-Dong CHEN Ju-Lin XING Wei PANG Li-Ye PAN

Affiliation: Guangdong Yi Fang Pharmaceutical Co.,Ltd, Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granule, Foshan 528244, Guangdong Province, China

Keywords: Gypsum Fibrosum Anemarrhenae Rhizoma Inductively coupled plasma mass spectrometry Grey correlation analysis Technique for order preference by similarity to an ideal solution

DOI: 10.12173/j.issn.1008-049X.202209417

Reference: Xiao-Dong YANG, Guo-Wei LI, Wen-Ping WU, Xiao-Lin LIU, Xiang-Dong CHEN, Ju-Lin XING, Wei PANG, Li-Ye PAN.Effects of Anemarrhenae Rhizoma on the dissolution of 6 inorganic elements in Gypsum Fibrosum under different compatibility ratio based on grey correlation analysis and TOPSIS model[J].Zhongguo Yaoshi Zazhi,2023,26(11):346-354.DOI: 10.12173/j.issn.1008-049X.202209417.[Article in Chinese]  Copied

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Abstract

Objective To discuss the effect of Anemarrhenae Rhizoma with different proportions on the dissolution of 6 inorganic elements (K, Ti, Sr, Ba, Ca, Mg) in Gypsum Fibrosum under different compatibility based on grey correlation analysis and technique for order preference by similarity to an ideal solution (TOPSIS) method and to provide reference for clinical application.

Methods Inductively coupled plasma mass spectrometry (ICP-MS) was established for simultaneous analysis of inorganic elements K, Ti, Sr, Ba, Ca, Mg in Gypsum Fibrosum - Anemarrhenae Rhizoma. The gray correlation ananlysis and TOPSIS method were used to comprehensively analyze the changes of six inorganic elements in Gypsum Fibrosum under different compatibility.

Results The findings of the ICP-MS determination of inorganic elements in Gypsum Fibrosum - Anemarrhenae Rhizoma were good in terms of linearity, precision, repeatability and stability. The average recovery was 81.78%-104.13%, and the RSD was 2.10%-4.62% (n=6). The dissolution of six inorganic elements in Gypsum Fibrosum after compatibility with different proportions of Anemarrhena Rhizoma was significantly higher than that of Gypsum Fibrosum single decoction (P<0.05). The dissolution scores of six inorganic elements in Gypsum Fibrosum were the highest when the compatibility proportion of Gypsum Fibrosum - Anemarrhenae Rhizoma was 30∶9.

Conclusion ICP-MS is a sensitive and accurate method for determining K, Ti, Sr, Ba, Ca and Mg in Gypsum Fibrosum- Anemarrhenae Rhizoma. The best compatibility ratio of Gypsum Fibrosum - Anemarrhenae Rhizoma is 30∶9, which can effectively improve the dissolution of six inorganic elements in Gypsum Fibrosum, and provide the basis for the further compatibility study of Gypsum Fibrosum and Anemarrhenae Rhizoma.

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