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Center for Evidence-Based and Translational Medicine of Wuhan University
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加味增液汤HPLC指纹图谱及3种主要成分的含量测定
LIU Shiqi
WU Chuang
ZHU Zhimin
XU Feng
CHANG Yaowen
ZHANG Haiyan
GOU Xiaojun
DOI:10.12173/j.issn.1008-049X.202311200
Modified Zengye Decoction
Ferulic acid
Aurantiamarin
Harpagoside
High performance liquid chromatography
Fingerprint
Content determination
Quality control
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基于化学计量学结合差异成分定量的小儿麻甘颗粒质量分析
FEI Yiqin
LYU Pan
YANG Ping
ZHAN Fangling
XU Ling
DOI:10.12173/j.issn.1008-049X.202401049
Xiao’er Magan granules
Chemometrics
Fingerprints
Difference analysis of component content
Ultra-performance liquid chromatography/quadrupole time-of-flight-tandem mass spectrometry
Quality analysis
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桦褐孔菌的生药学鉴别研究
ZHU Tianmi
DUAN Yuqing
WANG Simeng
CHEN Shuhe
YANG Ying
CHEN Keli
DOI:10.12173/j.issn.1008-049X.202312062
Inonotus obliquus
Medicinal parts
Basal source investigation
Trait identification
Microscopic identification
Molecular biology
High-performance liquid chromatography
Content determination
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加味藿香正气丸特征图谱建立及3种成分测定
ZHANG Yichang
FAN Xiaolei
SONG Defang
DOI:10.12173/j.issn.1008-049X.202310105
Modified Huoxiang Zhengqi pills
High performance liquid chromatography characteristic chromatogram
Hesperidin
Honokiol
Magnolol
Content determination
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超高效液相色谱-串联质谱法测定白术中34种禁限用农药残留
WANG Chenglin
XU Huibo
ZHANG Xuebin
GAO Haibo
LI Zhaokui
DOI:10.12173/j.issn.1008-049X.202403120
Atractylodes
Pesticide residues
Matrix
Ultra performance liquid chromatography tandem mass spectrometry
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基于HPLC-Q-Exactive MS和网络药理学探讨红花清肝十三味丸治疗非酒精性脂肪肝的药效物质基础及作用机制
HAO Xia
LIU Jing
ZHANG Qian
LI Jun
DOI:10.12173/j.issn.2097-4922.202403139
Honghua Qinggan Shisanwei pills
Non-alcoholic fatty liver disease
High performance liquid chromatography-Q-Exactive mass spectrometry
Network pharmacology
Molecular docking
Insulin resistance
Oxidative stress
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UPLC-MS/MS测定生脉饮中麦冬及其掺伪品的3种特征成分
HUANG Saiyan
XU Danyang
YAO Yiran
WANG Shu
QIAN Jie
ZHU Lin
LIU Huanhuan
DOI:10.12173/j.issn.2097-4922.202403050
Shengmaiyin
Ophiopogon japonicus
Methylophiopogonanone A
Liriopeside B
Liriope muscari baily saponin C
Ultra performance liquid chromatography tandem mass spectrometry
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基于UPLC指纹图谱和多指标成分定量的罗汉果标准汤剂质量评价
ZHANG Fangping
WEI Cuijie
LIU Xiaoxia
XIE Wenkai
CHEN Yuanyuan
DUAN Zhiwen
FENG Yongwei
HE Minyou
CHEN Roushan
SUN Dongmei
ZHOU Lin
LI Zhenyu
DOI:10.12173/j.issn.2097-4922.202406102
Siraitiae fructus
Standard decoction
Ultra performance liquid chromatography
Fingerprint
Content determination
Quality markers
Kaempferol
Chemometrics
Quality evaluation
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丙酸倍氯米松吸入气雾剂中新杂质的定性定量分析
DAI Cong
TIAN Heng
WU Chunmin
YANG Yixue
BEI Qihua
YAN Quanhong
DOI:10.12173/j.issn.2097-4922.202403196
Beclomethasone propionate inhalation aerasol
Ultra-performance liquid chromatography-Q-exactive orbitrap-mass spectrometry
Discovery Studio software
New impurity
Identification
Toxicity prediction
Content determination
Details
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HPLC-MS/MS法测定白血病患者血浆奥雷巴替尼的方法学研究及临床应用
GUO Jinyan
SUN Wenli
LIU Rui
LU Guangze
LIU Hongxing
WANG Lei
DOI:10.12173/j.issn.2097-4922.202405061
Olverembatinib
High-performance liquid chromatography tandem mass spectrometry
Therapeutic drug monitoring
Leukemia
Methodological study
Chinical application
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夫西地酸涂膜剂的制备工艺与透皮吸收研究
CHEN Hui
CAI Li
NING Lin
LUO Chunmei
DOI:10.12173/j.issn.2097-4922.202404185
Fusidic acid film
Preparation process
Response surface methodology
Transdermal absorption
High-performance liquid chromatography
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超滤离心-HPLC法测定鲁索替尼固体脂质纳米粒的包封率
FENG Shiquan
YU Jiaqi
DONG Deqiao
GAN Changran
PENG Haoyang
DUAN Chengcheng
QIN Zhenmiao
GAO Yanan
DOI:10.12173/j.issn.2097-4922.202406146
Ruxolutinib
Solid lipid nanoparticles
Melt-emulsification ultrasonic method
High performance liquid chromatography
Ultrafiltration centrifugation
Encapsulation rate
Methodology
Details
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基于HPLC-QAMS多指标成分联合OPLS-DA及加权TOPSIS模型的威灵仙药材质量评价
FENG Xiaochuan
ZHANG Jing
XU Yanzhao
ZHANG Rui
DOI:10.12173/j.issn.2097-4922.202406118
Clematidis radix et rhizoma
High-performance liquid chromatography
Stechiometry
Principal component analysis
Orthogonal partial least squares discriminant analysis
Weighted TOPSIS method
Quality evaluation
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基于UPLC-Q-Exactive-MS技术鉴定接骨七厘片的化学成分及血中移行成分
FANG Xiaoyang
ZHOU Rongrong
SHEN Bingbing
HE Weiwei
XIAO Jie
XU Jin
ZENG Hongliang
ZHANG Shuihan
DOI:10.12173/j.issn.2097-4922.202404200
Jiegu Qili tablets
Component analysis
Medicated serum
Ultra performance liquid chromatography-quadrupole-exactive-mass spectrometry
Chemical composition
Metabolites
Blood components
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LC-MS/MS测定枸橼酸西地那非中磺酸酯类基因毒性杂质
LI Cuifen
LI Jianhua
CHEN Xinguo
RUAN Pengwu
QIN Fei
DOI:10.12173/j.issn.2097-4922.202405143
Sildenafil citrate
Genotoxic impurity
Suifonate ester
Ethyl 4-ethoxy-3-formylbenzenesulfonate
High performance liquid chromatography mass spectromete
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