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Research progress on the pharmacological effects and mechanisms of Bletilla striata in promoting diabetic foot ulcer healing

Published on Jan. 01, 2026Total Views: 11 times Total Downloads: 1 times Download Mobile

Author: SUN Ping 1 ZHANG Yufeng 1 LI Chenxia 1 ZHANG Chenning 1, 2

Affiliation: 1. Department of Endocrinology, Postgraduate Union Training Base of Xiangyang No.1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang 441000, Hubei Province, China 2. Jiangsu Kanion Pharmaceutical Co., Ltd, Lianyungang 222001, Jiangsu Province, China

Keywords: Bletilla striata Diabetic foot ulcer Pharmacological effects Research progress Wound healing Hyperglycemia Hemostasis

DOI: 10.12173/j.issn.2097-4922.202503066

Reference: SUN Ping, ZHANG Yufeng, LI Chenxia, ZHANG Chenning. Research progress on the pharmacological effects and mechanisms of Bletilla striata in promoting diabetic foot ulcer healing[J]. Yaoxue QianYan Zazhi, 2025, 29(12): 2123-2136. DOI: 10.12173/j.issn.2097-4922.202503066.[Article in Chinese]

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Abstract

Diabetic foot ulcer (DFU) is one of the most common and severe complications of diabetes, significantly impacting patients' quality of life. Due to factors such as hyperglycemia, vascular pathology and neuropathy, the wound-healing capacity of diabetic patients is markedly impaired, leading to persistent and non-healing ulcerative wounds. Bletilla striata (Baiji), a traditional Chinese herb, has demonstrated remarkable efficacy in astringent, strop bleeding, resolving swelling and tissue regeneration, showing high potential in the field of chronic wound repair. To further explore the active components, pharmacological effects, mechanisms, and research progress of Bletilla striata in promoting the healing of diabetic foot ulcers, this review summarizes recent domestic and international studies, aiming to provide references for clinical applications and future research.

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References

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