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Vol 29,2025 No.12
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Vol 29,2025
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Contents
Vol 29,2025 No.12
Date of publication: December 25, 2025
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Vol 29,2025 No.11
Integrated network pharmacology and molecular docking to explore the potential molecular mechanisms of diosmin against prostatic hyperplasia complicated with chronic prostatitis
TANG Liu
JIANG Xiao
LUO Guangwen
WANG Lei
2025,29(12):1981-1989
Diosmin
Benign prostatic hyperplasia
Chronic prostatitis
Network pharmacology
Molecular docking
Signaling pathway
GO funnction analysis
KEGG pathway analysis
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Investigating the effects of silibinin on proliferation, apoptosis, migration, invasion, and ferroprelation of HepG2 hepatocellular carcinoma cells based on network pharmacology
DING Houwei
SHENG Hua
ZHANG Ping
CHEN Meihui
2025,29(12):1990-1999
Silibinin
Liver cancer
Cell proliferation
Cell apoptosis
Cell migration
Cell invasion
Ferroptosis
Network pharmacology
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The multi-target mechanism of Portulaca oleracea's hypoglycemic effect: network pharmacology prediction and molecular docking analysis
HU Pingping
XIA Wei
LI Yanpeng
CHEN Ting
HE Juan
2025,29(12):2000-2008
Portulaca oleracea
Hypoglycaemia
Network pharmacology
Molecular docking
Quercetin
Kaempferol
IL-6
TNF
AKT1
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Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway
WANG Dui
DANG Lijuan
ZHANG Qiang
ZHAO Xiaobin
LI Xiaoyu
ZHANG Zhengfeng
2025,29(12):2009-2016
Astragalus polysaccharides
Doxorubicin
Myocardial injury
TGF-β1/Smad3 signaling pathway
Traditional Chinese medicine
AC16
Cardiomyocytes
Apoptosis
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Optimization and verification of the inclusion process of volatile oil from Xinyi Tongqiao granules
ZHU Yuyan
LI Ting
HUANG Zhijun
ZHOU Qi
2025,29(12):2017-2026
Xinyi Tongqiao granules
β-cyclodextrin
Inclusion complexes
Volatile oils
Patchouli alcohol
Saturated water solution method
Characterization
Orthogonal test
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Construction of a shortage risk early warning model based on risk matrix evaluation and Bayesian belief propagation neural network
SUN Yiyuan
LIU Junjiao
NI Ying
LIANG Liangliang
LIU Yunmei
ZHAO Guohong
ZHANG Jingbo
YANG Yang
LI Qiang
2025,29(12):2027-2035
Drug shortage
Drug use monitoring
Risk warning
Signal detection
Bayesian confidence propagation neural network
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Effective analysis of adverse drug events and toxicological mechanisms of octreotide based on the FAERS database and network toxicology
WANG Changwen
WANG Huiru
XU Shibo
SUN Fanfan
YAN Junzhen
2025,29(12):2036-2045
Octreotide
Adverse drug events
Network toxicology
Signal mining
FAERS
Tumor necrosis factor
Ransforming growth factor β
Protein-protein interaction
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Research hotspots and trends of Gardenia jasminoides based on bibliometric analysis
HU Siqi
HONG Hailan
LIU Wei
ZHU Jizhou
WAN Na
LIU Hongqin
WANG Fenghuan
LI Hui
2025,29(12):2046-2055
Gardenia jasminoides
Bibliometrics
Research status
Hotspot analysis
CiteSpace
Pharmacological effects
Traditional Chinese medicine
Network pharmacology
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Pharmacovigilance analysis of drug-related extrapyramidal symptoms based on the FAERS database
WU Lihua
WANG Huiying
CHEN Yangyi
PAN Lu
RAO Mei
2025,29(12):2056-2064
Drug related extrapyramidal symptoms
Adverse drug reactions
Pharmacovigilance
Signal Mining
FAERS database
Logistic regression
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Analysis of the impact of international research on dose rounding of anti-tumor drugs on the cost of anti-tumor drugs in China
REN Lingzhi
YU Wenhao
WANG Ting
TANG Min
ZHOU Ziyuan
TANG Haochun
MENG Jun
2025,29(12):2065-2071
Anti-tumor drugs
Dose rounding
Drug cost
Cost saving
Healthcare expenses
Economic burden
Monoclonal antibody
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Thoughts on future smart shared traditional Chinese medicine pharmacy based on the construction practice of regional shared traditional Chinese medicine pharmacy in Hangzhou
YANG Fanlin
LIU Guoxiu
SUN Qianqian
LI Chunjin
CHEN Hongmei
GUO Junping
ZHAI Huaqiang
2025,29(12):2072-2079
Regional shared traditional Chinese medicine pharmacy
Hangzhou
Construction practice
Smart shared traditional Chinese medicine pharmacy
Traditional Chinese medicine service
Questionnaire survey
Pharmaceutical administration
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Artificial intelligence reshapes hospital pharmacy practice: advances in application and real-world challenges
FANG Haiyan
HE Qing
2025,29(12):2080-2087
Artificial intelligence
Hospital pharmacy
Machine learning
Natural language processing
Deep learning
Big data
Rational use of drug
Drug administration
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Research on quality management, responsibilities and regulatory measures of the domestic responsible person for drugs
WANG Ying
WANG Guangping
2025,29(12):2088-2097
Imported drugs
Domestic responsible entity
Overseas marketing authorization holders
Quality management responsibility
Responsible entity
Obligation
Challenge
Supervision
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Research progress on the chemical constituents and pharmacological effects of Chinese yam
ZHENG Xiaonan
SUN Cuige
DI Qing
HU Liping
ZHAO Xiangxuan
2025,29(12):2098-2111
Chinese yam
Chemical composition
Pharmacological effects
Chronic atrophic gastritis
Drug target
Network pharmacology
Targeted drugs
Natural products
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Research progress of the chemical composition and pharmacological effects of Gastrodia elata Bl.
LIU Zhenzhen
YAN Jingyi
LI Ganpeng
LIU Xin
REN Feng
2025,29(12):2112-2122
Gastrodia elata Bl.
Chemical composition
Gastrodin
Polysaccharide
Organic acids
Sterol
Pharmacological effect
Protective effect
Research progress
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Research progress on the pharmacological effects and mechanisms of Bletilla striata in promoting diabetic foot ulcer healing
SUN Ping
ZHANG Yufeng
LI Chenxia
ZHANG Chenning
2025,29(12):2123-2136
Bletilla striata
Diabetic foot ulcer
Pharmacological effects
Research progress
Wound healing
Hyperglycemia
Hemostasis
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Research progress in the treatment of simple obesity with traditional Chinese medicine compounds
ZHANG Xiali
WANG Zhuo
MI Li
2025,29(12):2137-2144
Simple obesity
Traditional Chinese medicine compounding
Research progress
Leptin resistance
Insulin resistance
Gut microbiota dysbiosis
JAK2-STAT3 signaling pathway
PI3K/Akt signaling pathway
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Application progress of paraben preservatives in pharmaceutical preparations
YI Qiao
WANG Jie
YAN Leina
2025,29(12):2145-2153
Paraben
Antimicrobial effectiveness
Safety
Methylparaben
Ethylparaben
Bacteriostat
Dosage
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Application of hot stage polarizing microscope in the study of drug polymorphism
CHEN Hui
WANG Huijie
ZHANG Shibo
LI Yao
WANG Huan
ZHOU Hao
2025,29(12):2154-2160
Hot stage polarizing microscope
Drug polymorphism
Characterization of polymorphism
Control of polymorphism
In-situ research
Crystal habit analysis
Phase transition kinetics
Process optimization
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