Vol 29,2025 No.12

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Date of publication: December 25, 2025

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Vol 29,2025 No.11

Integrated network pharmacology and molecular docking to explore the potential molecular mechanisms of diosmin against prostatic hyperplasia complicated with chronic prostatitis

TANG Liu JIANG Xiao LUO Guangwen WANG Lei

2025,29(12):1981-1989

Diosmin Benign prostatic hyperplasia Chronic prostatitis Network pharmacology Molecular docking Signaling pathway GO funnction analysis KEGG pathway analysis
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Investigating the effects of silibinin on proliferation, apoptosis, migration, invasion, and ferroprelation of HepG2 hepatocellular carcinoma cells based on network pharmacology

DING Houwei SHENG Hua ZHANG Ping CHEN Meihui

2025,29(12):1990-1999

Silibinin Liver cancer Cell proliferation Cell apoptosis Cell migration Cell invasion Ferroptosis Network pharmacology
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The multi-target mechanism of Portulaca oleracea's hypoglycemic effect: network pharmacology prediction and molecular docking analysis

HU Pingping XIA Wei LI Yanpeng CHEN Ting HE Juan

2025,29(12):2000-2008

Portulaca oleracea Hypoglycaemia Network pharmacology Molecular docking Quercetin Kaempferol IL-6 TNF AKT1
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Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway

WANG Dui DANG Lijuan ZHANG Qiang ZHAO Xiaobin LI Xiaoyu ZHANG Zhengfeng

2025,29(12):2009-2016

Astragalus polysaccharides Doxorubicin Myocardial injury TGF-β1/Smad3 signaling pathway Traditional Chinese medicine AC16 Cardiomyocytes Apoptosis
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Optimization and verification of the inclusion process of volatile oil from Xinyi Tongqiao granules

ZHU Yuyan LI Ting HUANG Zhijun ZHOU Qi

2025,29(12):2017-2026

Xinyi Tongqiao granules β-cyclodextrin Inclusion complexes Volatile oils Patchouli alcohol Saturated water solution method Characterization Orthogonal test
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Construction of a shortage risk early warning model based on risk matrix evaluation and Bayesian belief propagation neural network

SUN Yiyuan LIU Junjiao NI Ying LIANG Liangliang LIU Yunmei ZHAO Guohong ZHANG Jingbo YANG Yang LI Qiang

2025,29(12):2027-2035

Drug shortage Drug use monitoring Risk warning Signal detection Bayesian confidence propagation neural network
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Effective analysis of adverse drug events and toxicological mechanisms of octreotide based on the FAERS database and network toxicology

WANG Changwen WANG Huiru XU Shibo SUN Fanfan YAN Junzhen

2025,29(12):2036-2045

Octreotide Adverse drug events Network toxicology Signal mining FAERS Tumor necrosis factor Ransforming growth factor β Protein-protein interaction
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Research hotspots and trends of Gardenia jasminoides based on bibliometric analysis

HU Siqi HONG Hailan LIU Wei ZHU Jizhou WAN Na LIU Hongqin WANG Fenghuan LI Hui

2025,29(12):2046-2055

Gardenia jasminoides Bibliometrics Research status Hotspot analysis CiteSpace Pharmacological effects Traditional Chinese medicine Network pharmacology
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Pharmacovigilance analysis of drug-related extrapyramidal symptoms based on the FAERS database

WU Lihua WANG Huiying CHEN Yangyi PAN Lu RAO Mei

2025,29(12):2056-2064

Drug related extrapyramidal symptoms Adverse drug reactions Pharmacovigilance Signal Mining FAERS database Logistic regression
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Analysis of the impact of international research on dose rounding of anti-tumor drugs on the cost of anti-tumor drugs in China

REN Lingzhi YU Wenhao WANG Ting TANG Min ZHOU Ziyuan TANG Haochun MENG Jun

2025,29(12):2065-2071

Anti-tumor drugs Dose rounding Drug cost Cost saving Healthcare expenses Economic burden Monoclonal antibody
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Thoughts on future smart shared traditional Chinese medicine pharmacy based on the construction practice of regional shared traditional Chinese medicine pharmacy in Hangzhou

YANG Fanlin LIU Guoxiu SUN Qianqian LI Chunjin CHEN Hongmei GUO Junping ZHAI Huaqiang

2025,29(12):2072-2079

Regional shared traditional Chinese medicine pharmacy Hangzhou Construction practice Smart shared traditional Chinese medicine pharmacy Traditional Chinese medicine service Questionnaire survey Pharmaceutical administration
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Artificial intelligence reshapes hospital pharmacy practice: advances in application and real-world challenges

FANG Haiyan HE Qing

2025,29(12):2080-2087

Artificial intelligence Hospital pharmacy Machine learning Natural language processing Deep learning Big data Rational use of drug Drug administration
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Research on quality management, responsibilities and regulatory measures of the domestic responsible person for drugs

WANG Ying WANG Guangping

2025,29(12):2088-2097

Imported drugs Domestic responsible entity Overseas marketing authorization holders Quality management responsibility Responsible entity Obligation Challenge Supervision
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 Contents

Vol 29,2025 No.12

Vol 29,2025 No.11

Integrated network pharmacology and molecular docking to explore the potential molecular mechanisms of diosmin against prostatic hyperplasia complicated with chronic prostatitis

Investigating the effects of silibinin on proliferation, apoptosis, migration, invasion, and ferroprelation of HepG2 hepatocellular carcinoma cells based on network pharmacology

The multi-target mechanism of Portulaca oleracea's hypoglycemic effect: network pharmacology prediction and molecular docking analysis

Exploring the effect of astragalus polysaccharides on adriamycin-induced apoptosis of AC16 cardiomyocytes based on the TGF-β1/Smad3 signaling pathway

Optimization and verification of the inclusion process of volatile oil from Xinyi Tongqiao granules

Construction of a shortage risk early warning model based on risk matrix evaluation and Bayesian belief propagation neural network

Effective analysis of adverse drug events and toxicological mechanisms of octreotide based on the FAERS database and network toxicology

Research hotspots and trends of Gardenia jasminoides based on bibliometric analysis

Pharmacovigilance analysis of drug-related extrapyramidal symptoms based on the FAERS database

Analysis of the impact of international research on dose rounding of anti-tumor drugs on the cost of anti-tumor drugs in China

Thoughts on future smart shared traditional Chinese medicine pharmacy based on the construction practice of regional shared traditional Chinese medicine pharmacy in Hangzhou

Artificial intelligence reshapes hospital pharmacy practice: advances in application and real-world challenges

Research on quality management, responsibilities and regulatory measures of the domestic responsible person for drugs

Research progress on the chemical constituents and pharmacological effects of Chinese yam

Research progress of the chemical composition and pharmacological effects of Gastrodia elata Bl.

Research progress on the pharmacological effects and mechanisms of Bletilla striata in promoting diabetic foot ulcer healing

Research progress in the treatment of simple obesity with traditional Chinese medicine compounds

Application progress of paraben preservatives in pharmaceutical preparations

Application of hot stage polarizing microscope in the study of drug polymorphism